MYP_125113
Filgrastim
Anticancer
Immunology
▸
Immune modulation
▸
Immunomodulatory activity
Therapeutic / Biomedical activity
▸
Enzyme replacement therapy
Standard
175 amino acids
C845H1343N223O243S9
Standard
MTPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP
18802.64 Da
5.65
-4.09
-4.66
-0.0234
0.21
0.71
0.19
60.50
104.91
0.0629
15470.00
15720.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
7303.96
-74.69
248.0
253.0
609.0
1320.0
31.0
191.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0193318
VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Escherichia coli [Bacterium]
Growth factor
9606;562
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
Immunomodulatory
Elimination half-life, healthy subjects and cancer patients, Neopogen = 3.5 hours
RECORD: Rec_0245726
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Escherichia coli [Bacterium]
PEGylated G-CSF
9606;562
Structure & Mods
linear peptide/protein therapeutic [Linear]
noncanonical stereochemical or chemical modification [Modified]
PEGylation
Bio-Activity Profile
Hematopoietic
G-CSF
Neutrophil recovery
15-80 h
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