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MYP_125102
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Basic Information
Gomesin [PYA1E]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C93H157N35O25S4
Standard
Sequence
ECRRLCYKQRCVTYCRGR
Physicochemical Analysis
2293.72 Da
9.58
4.79
4.56
0.2663
-1.06
0.47
-0.64
65.19
37.78
0.1111
2980.00
3230.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1034.62
-11.45
44.0
34.0
77.0
157.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015198 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Amidation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30068931 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30068931/
RECORD: Rec_0030086 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Gomesin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperOctober 27, 2000 The Journal of Biological Chemistry, 275,33464-33470. | http://www.jbc.org/content/275/43/33464.full.html
RECORD: Rec_0040242 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Amidation
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30068931 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30068931/
RECORD: Rec_0051863 VERIFIED: YES
Provenance & Taxonomy
Acanthoscurria gomesiana [Animal]
Gomesin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
Breast cancer (cell line not reported)
PaperCancerPPD2 curated year-page record; primary PMID 10942757 (2000), additional curated PMID 18957441. PMID10942757;18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10942757/
RECORD: Rec_0091505 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
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