Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC787H1243N229O233S3

DescriptionStandard

        MVGINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPLIDRGDIRQAIDRCSNIWASLPGAGYGQYEHKIDSLIAKFKEAGGVVNETSL
    

Molecular Weight17736.88 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.34

Charge Density (pH 7.0) 0.0302

GRAVY Index-0.58

Hydrophobic Moment 0.68

Boman Index-0.09

Instability Index20.29

Aliphatic Index 82.78

Aromaticity 0.0886

Extinction Coeff. Reduced 30940.00

Extinction Coeff. Oxidized 30940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7536.31

LogP -76.54

H-bond Donors 263.0

H-bond Acceptors 244.0

Rotatable Bonds 599.0

Heavy Atoms 1252.0

Ring Count 26.0

Amide Bonds 173.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133937 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage HK106 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic