Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length200 amino acids

Chemical FormulaC1014H1544N226O306S11

DescriptionStandard

        CNILYLALPITLTVATPVDDLAEVDYSLNRFPAVFQPFIDLDLKGTVFPAGNYTDSPYMAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGSIIPEVAKYSVIPYPVMLKLMATEIPVISLEKDSFTVDIEGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNR
    

Molecular Weight22149.15 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-15.24

Net Charge (pH 7.4) -15.54

Charge Density (pH 7.0) -0.0762

GRAVY Index0.36

Hydrophobic Moment 0.55

Boman Index0.26

Instability Index50.18

Aliphatic Index 96.10

Aromaticity 0.1300

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8391.38

LogP -99.10

H-bond Donors 285.0

H-bond Acceptors 302.0

Rotatable Bonds 701.0

Heavy Atoms 1557.0

Ring Count 39.0

Amide Bonds 214.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384123 VERIFIED: NO

Provenance & Taxonomy

OrganismSapayoa aenigma [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria