‹ ›
MYP_125079
← PREVIOUS NEXT → BACK
Basic Information
Rs-AFP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
51 amino acids
C242H372N74O70S8
Standard
Sequence
QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
Physicochemical Analysis
5694.52 Da
8.72
3.85
3.42
0.0756
-0.45
0.42
-0.06
36.04
47.84
0.0980
8480.00
8980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2333.68
-28.37
86.0
84.0
182.0
394.0
11.0
58.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0086050 VERIFIED: YES
Provenance & Taxonomy
Raphanus sativus [Plant]
Defensin
3726
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
Alternaria brassicola
15 μg/mL
IC50
PaperPubMed PMID 1639777 | PubMed PMID 7780308 | PubMed PMID 9000000 PMID1639777;7780308;9000000;16397777;78030;89000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1639777/
RECORD: Rec_0106594 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
4-51, 15-36, 21-45, 25-47
Bio-Activity Profile
Antimicrobial Antifungal
Pyricularia oryzae
0.5 μg/mL
MIC
PMID8422949;8836771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0131917 VERIFIED: YES
Provenance & Taxonomy
Radish seeds [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
N-terminus is pyroglutamate
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum f.sp. lycopersici
30 μg/mL
IC50
PaperA new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
RECORD: Rec_0141533 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
4-51, 15-36, 21-45, 25-47
Bio-Activity Profile
Antimicrobial Antifungal
Botrytis cinerea
1.8 μg/mL
MIC
PMID8422949;8836771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0141990 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
4-51, 15-36, 21-45, 25-47
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum f
PMID8422949;8836771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
FIRST PREV 1 2 3 4 5 ... 11 NEXT LAST
Showing 5 records on this page · Page 3 of 11