Peptide Database

Peptide NameRs-AFP1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC242H372N74O70S8

DescriptionStandard

        QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
    

Molecular Weight5694.52 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)3.85

Net Charge (pH 7.4) 3.42

Charge Density (pH 7.0) 0.0756

GRAVY Index-0.45

Hydrophobic Moment 0.42

Boman Index-0.06

Instability Index36.04

Aliphatic Index 47.84

Aromaticity 0.0980

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2333.68

LogP -28.37

H-bond Donors 86.0

H-bond Acceptors 84.0

Rotatable Bonds 182.0

Heavy Atoms 394.0

Ring Count 11.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422989 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal

TargetStaphylococcus aureus

Activity6.25 μM

MethodMIC

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