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MYP_125079
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Basic Information
Rs-AFP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
51 amino acids
C242H372N74O70S8
Standard
Sequence
QKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
Physicochemical Analysis
5694.52 Da
8.72
3.85
3.42
0.0756
-0.45
0.42
-0.06
36.04
47.84
0.0980
8480.00
8980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2333.68
-28.37
86.0
84.0
182.0
394.0
11.0
58.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000026 VERIFIED: YES
Provenance & Taxonomy
Radish seeds [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamate
N-terminus is pyroglutamate
Bio-Activity Profile
Antimicrobial Antifungal
Verticillium dahliae
5 μg/mL
IC50
PaperA new family of basic cysteine-rich plant antifungal proteins from Brassicaceae species.
RECORD: Rec_0000282 VERIFIED: YES
Provenance & Taxonomy
Raphanus sativus var. niger [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
[PubMed ID : 7780308 - A. brassicola
20
IC50
PMID7780308;1639777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7780308/
RECORD: Rec_0001003 VERIFIED: NO
Provenance & Taxonomy
Brassica juncea [Plant]
Defensin
3707
Structure & Mods
gene-encoded linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Non-hemolytic Non-ribosomal
Evidence URLhttps://www.uniprot.org/uniprotkb/E3WAM6/entry
RECORD: Rec_0019469 VERIFIED: YES
Provenance & Taxonomy
Sinapis alba [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Cyclization
None
4-51, 15-36, 21-45, 25-47
Bio-Activity Profile
Antimicrobial Antifungal
NOTE: In synthetic low ionic strength fungal growth medium
PMID8422949;8836771 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8422949/
RECORD: Rec_0022274 VERIFIED: YES
Provenance & Taxonomy
Raphanus sativus var. niger [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
[PubMed ID : 7780308 - A. brassicola
8
IC50
PMID7780308;1639777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7780308/
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