Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC222H360N58O74S5

DescriptionStandard

        MKNSKDVLNNAIEEVSEKELMEVAGGKKGPGWIATITDDCPNSIFVCC
    

Molecular Weight5185.90 Da

Isoelectric Point (pI)4.55

Net Charge (pH 7.0)-3.52

Net Charge (pH 7.4) -3.79

Charge Density (pH 7.0) -0.0733

GRAVY Index-0.19

Hydrophobic Moment 0.56

Boman Index0.05

Instability Index35.37

Aliphatic Index 79.17

Aromaticity 0.0417

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2131.24

LogP -22.42

H-bond Donors 73.0

H-bond Acceptors 76.0

Rotatable Bonds 176.0

Heavy Atoms 359.0

Ring Count 5.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321240 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus salivarius [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0399644 VERIFIED: NO