Peptide Database

Peptide NameCath-A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC207H354N60O39

DescriptionStandard

        KRFKKFFRKLKKSVKKRKKEFKKKPRVIKVSIPF
    

Molecular Weight4307.40 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)16.75

Net Charge (pH 7.4) 16.52

Charge Density (pH 7.0) 0.4926

GRAVY Index-1.22

Hydrophobic Moment 0.90

Boman Index-0.56

Instability Index9.59

Aliphatic Index 60.00

Aromaticity 0.1471

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1695.68

LogP -8.56

H-bond Donors 62.0

H-bond Acceptors 56.0

Rotatable Bonds 161.0

Heavy Atoms 306.0

Ring Count 7.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046228 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetPS-45

Activity32 μg/mL

MethodMIC

RECORD: Rec_0051501 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 25923

Activity16 μg/mL

MethodMIC

RECORD: Rec_0057713 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic

PaperThe antimicrobial potential of a new derivative of cathelicidin from Bungarus fasciatus against methicillin-resistant Staphylococcus aureus. J Microbiol. 2018 Feb;56(2):128-137. doi: 10.1007/s12275-018-7444-5. PMID: 29392557. PMID29392557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29392557/

RECORD: Rec_0060986 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC 25923

Activity32 μg/mL

MethodMIC

PaperThe antimicrobial potential of a new derivative of cathelicidin from Bungarus fasciatus against methicillin-resistant Staphylococcus aureus. J Microbiol. 2018 Feb;56(2):128-137. doi: 10.1007/s12275-018-7444-5. PMID: 29392557. PMID29392557 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29392557/

RECORD: Rec_0062848 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella pneumoniae ATCC 13883

Activity16 μg/mL

MethodMIC

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