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MYP_125027
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Basic Information
P1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C73H124N22O24S2
Standard
Sequence
DTRACDVIALLCHLNT
Physicochemical Analysis
1758.03 Da
5.21
-1.17
-1.45
-0.0731
0.57
0.42
0.12
54.55
128.12
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
748.55
-7.77
28.0
26.0
56.0
121.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0242995 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Library-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
West Nile virus (Virus entry); Vero
qPCR
PaperAntiviral peptides targeting the west nile virus envelope protein. | Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. | J Virol. 2007 | PMID:17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0255626 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0302020 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Dengue virus serotype 2:inhibition of virus infection in Vero cells
99.3±0.7 %
Inhibition
PaperPubMed PMID: 17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0334109 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
toxicity against Vero cells up to 500μM
500 μM
Cytotoxicity
PaperPubMed PMID: 17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
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