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MYP_125027
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Basic Information
P1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Dengue virus
Antiviral ▸ Anti-Flavivirus ▸ Anti-West Nile virus
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C73H124N22O24S2
Standard
Sequence
DTRACDVIALLCHLNT
Physicochemical Analysis
1758.03 Da
5.21
-1.17
-1.45
-0.0731
0.57
0.42
0.12
54.55
128.12
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
748.55
-7.77
28.0
26.0
56.0
121.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027082 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PaperPubMed PMID: 17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0098771 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
west nile virus(WNV):inhibition of virus infection in Vero cells
67.0±0.1 μM
IC50
PaperPubMed PMID: 17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0099838 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-WNV Entry inhibition
West nile virus(WNV) | Vero cells
67±0.1 μM
IC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: >10 h
PaperAntiviral peptides targeting the west nile virus envelope protein. | Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. | J Virol. 2007 Feb;81(4):2047-55. | DOI:10.1128/JVI.01840-06 | PMID:17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0150845 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-DENV Entry inhibition
Dengue virus serotype 2 | Vero cells
200 μM
% inhibition
Mammalian: 1.1 h; Yeast: 3 min; E. coli: >10 h
PaperAntiviral peptides targeting the west nile virus envelope protein. | Bai F, Town T, Pradhan D, Cox J, Ashish, Ledizet M, Anderson JF, Flavell RA, Krueger JK, Koski RA, Fikrig E. | J Virol. 2007 Feb;81(4):2047-55. | DOI:10.1128/JVI.01840-06 | PMID:17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
RECORD: Rec_0241501 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 17151121 PMID17151121 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17151121/
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