Peptide Database

Peptide NameSLAY-screened peptide P3073

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC97H152N26O31S

DescriptionStandard

        TTTSLLSRLPPNYMAYSSAH
    

Molecular Weight2210.47 Da

Isoelectric Point (pI)8.29

Net Charge (pH 7.0)0.48

Net Charge (pH 7.4) 0.24

Charge Density (pH 7.0) 0.0242

GRAVY Index-0.27

Hydrophobic Moment 0.43

Boman Index0.06

Instability Index71.92

Aliphatic Index 68.50

Aromaticity 0.1000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 914.38

LogP -11.33

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 65.0

Heavy Atoms 155.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0329621 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/