MYP_124936
Basic Information
Wollamide B [D-Orn 6 IPr-D-Orn]
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
NVLLWX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0108830 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis H37Rv
6.25 μg/mL
MIC
RECORD: Rec_0120123 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus cereus ATCC 14579
50 μg/mL
MIC
RECORD: Rec_0125144 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
137.6 μM
IC50
RECORD: Rec_0137781 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial Antibacterial
Clostridioides difficile R20291
256 μg/mL
MIC
RECORD: Rec_0161095 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
l=D-Leu; X=Orn
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
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