MYP_124936
Wollamide B [D-Orn 6 IPr-D-Orn]
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Antimicrobial
▸
Antibacterial
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
not Standard
6 amino acids
-
contains X representing unresolved or non-standard residue
NVLLWX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0018392
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Hemolytic
Vero cells (IC50 at 223 microg/ml, Vero cells (IC50 at 73.2 microg/ml, Vero cells (IC50 at 405.4 microg/ml, Vero cells (IC50 at 398.6 microg/ml, Vero cells (IC50 at 403.2 microg/ml, Vero cells (IC50 at 105.7 microg/ml, Vero cells (IC50 at 89.2 microg/ml, Vero cells (IC50 at 190.5 microg/ml, Vero cells (IC50 at 86.4 microg/ml, Vero cells (IC50 at 42.2 microg/ml
50 μg/mL
Hemolysis
RECORD: Rec_0022738
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
l=D-Leu; X=Orn
Bio-Activity Profile
Antimicrobial
Anticancer
Hep-G2
137.6 μM
IC50
RECORD: Rec_0034403
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial
Antibacterial
Enterococcus faecium ATCC 19434
200 μg/mL
MIC
RECORD: Rec_0046044
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial
Antibacterial
Mycobacterium tuberculosis H37Rv
200 μg/mL
MIC
RECORD: Rec_0074367
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 6
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus aureus ATCC 29213
200 μg/mL
MIC
Showing 5 records on this page · Page 1 of 8