Peptide Database

Peptide NameVigno 2

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC116H183N35O43S6

DescriptionStandard

        GSSPLCGETCAGGTCNTPGCSCSWPVCVRD
    

Molecular Weight2948.29 Da

Isoelectric Point (pI)4.67

Net Charge (pH 7.0)-1.29

Net Charge (pH 7.4) -1.59

Charge Density (pH 7.0) -0.0431

GRAVY Index0.03

Hydrophobic Moment 0.28

Boman Index0.11

Instability Index41.45

Aliphatic Index 35.67

Aromaticity 0.0333

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1217.84

LogP -20.60

H-bond Donors 48.0

H-bond Acceptors 48.0

Rotatable Bonds 86.0

Heavy Atoms 200.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0197348 VERIFIED: YES

Provenance & Taxonomy

OrganismViola ignobilis [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Enzyme inhibitory Enzyme-inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme