Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC501H819N143O130S9

DescriptionStandard

        MKFLILFLAIFLIKEPMIPEPTCWMDGKCRLVCKNDEDTVVRCLNRKRCCVPSRYLTIQPVTIDSEPRWTLPLTFRPVRKKNKPAKRENKNINHG
    

Molecular Weight11214.33 Da

Isoelectric Point (pI)9.74

Net Charge (pH 7.0)9.54

Net Charge (pH 7.4) 9.15

Charge Density (pH 7.0) 0.1004

GRAVY Index-0.38

Hydrophobic Moment 0.66

Boman Index-0.13

Instability Index63.77

Aliphatic Index 86.11

Aromaticity 0.0737

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4416.57

LogP -34.66

H-bond Donors 158.0

H-bond Acceptors 150.0

Rotatable Bonds 371.0

Heavy Atoms 783.0

Ring Count 19.0

Amide Bonds 101.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224357 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic