Peptide Database

Peptide NameSLAY-screened peptide P5634

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC101H145N29O27S

DescriptionStandard

        PSASSAYHRYHSRSCLLFF
    

Molecular Weight2229.47 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)2.12

Net Charge (pH 7.4) 1.95

Charge Density (pH 7.0) 0.1116

GRAVY Index-0.23

Hydrophobic Moment 0.41

Boman Index-0.00

Instability Index99.33

Aliphatic Index 51.58

Aromaticity 0.2105

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 895.90

LogP -9.59

H-bond Donors 36.0

H-bond Acceptors 32.0

Rotatable Bonds 67.0

Heavy Atoms 158.0

Ring Count 7.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009388 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/