‹ ›
MYP_124852
← PREVIOUS NEXT → BACK
Basic Information
Ranatuerin-2Cb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
27 amino acids
C127H221N33O32S2
Standard
Sequence
GLFLDTLKGLAGKLLQGLKCIKAGCKP
Physicochemical Analysis
2786.45 Da
9.60
3.74
3.50
0.1384
0.43
0.56
0.19
-5.52
122.96
0.0370
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1041.85
-7.06
37.0
38.0
98.0
194.0
2.0
27.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0119722 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Ranatuerin
8404
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
20-25
Leu (25.9%). Disulfide bridge: C20,C25;
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
46 μM
MIC
PaperPeptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens. PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0121344 VERIFIED: YES
Provenance & Taxonomy
Lithobates calamitans [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
20-25
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
40.0 μM
MIC
PaperT. Halverson et al. / Peptides 21 (2000) 469-476. Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans Evidence URLhttps://www.uniprot.org/uniprotkb/P82879/entry
RECORD: Rec_0145052 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Ranatuerin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
2 μM
MIC
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0145483 VERIFIED: YES
Provenance & Taxonomy
Lithobates calamitans [Animal]
Ranatuerin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
20-25
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
2.0 μM
MIC
PaperT. Halverson et al. / Peptides 21 (2000) 469-476. Purification and characterization of antimicrobial peptides from the skin of the North American green frog Rana clamitans Evidence URLhttps://www.uniprot.org/uniprotkb/P82879/entry
RECORD: Rec_0151480 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Ranatuerin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
40 μM
MIC
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 2 of 4