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MYP_124852
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Basic Information
Ranatuerin-2Cb
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
27 amino acids
C127H221N33O32S2
Standard
Sequence
GLFLDTLKGLAGKLLQGLKCIKAGCKP
Physicochemical Analysis
2786.45 Da
9.60
3.74
3.50
0.1384
0.43
0.56
0.19
-5.52
122.96
0.0370
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1041.85
-7.06
37.0
38.0
98.0
194.0
2.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017207 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Ranatuerin
8404
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
20-25
Leu (25.9%). Disulfide bridge: C20,C25;
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus
40 μM
MIC
PaperPeptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens. PMID10651828 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10651828/
RECORD: Rec_0021806 VERIFIED: NO
Provenance & Taxonomy
Rana clamitans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0059008 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Ranatuerin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperPubMed PMID: 10822101 PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0076846 VERIFIED: YES
Provenance & Taxonomy
Rana clamitans [Animal]
Ranatuerin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
2 μg/mL
MIC
PaperPubMed PMID: 10822101 PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
RECORD: Rec_0081518 VERIFIED: YES
Provenance & Taxonomy
Lithobates clamitans [Animal]
Frog skin active peptide (FSAP); Ranatuerin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Candida albicans
PMID10822101 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10822101/
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