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MYP_124837
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Basic Information
ARs-N
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
22 amino acids
C132H195N39O27S2
Standard
Sequence
RRWCVYAYVRVRGVRVYAYVCW
Physicochemical Analysis
2824.34 Da
10.05
4.74
4.50
0.2153
0.18
0.48
-0.06
79.77
88.18
0.2727
16960.00
17085.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1096.42
-4.40
46.0
34.0
83.0
200.0
8.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0331677 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-21
Bio-Activity Profile
Antimicrobial
A-baumanii c.i
>16 μM
MIC
PaperRedesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization.
RECORD: Rec_0356119 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID31234579 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31234579/
RECORD: Rec_0356967 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-21
Bio-Activity Profile
Antimicrobial
S-aureus 710A or ATCC 25923 or MRSA ATCC 33591 or clinical c.i
>16 μM
MIC
PaperRedesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization.
RECORD: Rec_0382395 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli M15
16 μM
MIC
PMID31234579 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31234579/
RECORD: Rec_0425874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Arenicin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-21
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes EGD
8 μM
MIC
PaperRedesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization.
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