Peptide Database

Peptide NameBeta-defensin 106A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC329H527N85O90S8

DescriptionStandard

        MRTFLFLFAVLFFLTPAKNEFFDEKCGKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID
    

Molecular Weight7369.74 Da

Isoelectric Point (pI)8.77

Net Charge (pH 7.0)3.44

Net Charge (pH 7.4) 3.10

Charge Density (pH 7.0) 0.0529

GRAVY Index0.09

Hydrophobic Moment 0.59

Boman Index0.04

Instability Index11.52

Aliphatic Index 81.08

Aromaticity 0.1077

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2843.82

LogP -24.30

H-bond Donors 103.0

H-bond Acceptors 102.0

Rotatable Bonds 252.0

Heavy Atoms 512.0

Ring Count 9.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0008652 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo pygmaeus [Animal]

FamilyDefensin

Tax ID9600

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0311531 VERIFIED: NO