Peptide Database

Peptide NamePyrokinin-4

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC73H118N22O18

DescriptionStandard

        AELPQGLWVRPRLG
    

Molecular Weight1591.85 Da

Isoelectric Point (pI)9.64

Net Charge (pH 7.0)0.80

Net Charge (pH 7.4) 0.61

Charge Density (pH 7.0) 0.0570

GRAVY Index-0.25

Hydrophobic Moment 0.26

Boman Index0.02

Instability Index56.02

Aliphatic Index 111.43

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 644.02

LogP -3.83

H-bond Donors 22.0

H-bond Acceptors 19.0

Rotatable Bonds 48.0

Heavy Atoms 113.0

Ring Count 4.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104624 VERIFIED: YES

Provenance & Taxonomy

OrganismPachyphasma brandbergense [Animal]

FamilyPyrokinin

Tax ID1041430

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone

RECORD: Rec_0208815 VERIFIED: YES

Provenance & Taxonomy

OrganismPachyphasma brandbergense [Animal]

FamilyPyrokinin

Tax ID1041430

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Myotropic

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0228999 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/