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MYP_124814
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Basic Information
SP15D
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C86H135N29O13
Standard
Sequence
RWIRWVWRKKLR
Physicochemical Analysis
1783.18 Da
12.00
5.76
5.55
0.4798
-1.33
0.63
-0.60
106.53
89.17
0.2500
16500.00
16500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
730.43
-1.04
30.0
19.0
58.0
128.0
6.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0143787 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Hemolytic
human red blood cells
100 μg/mL
Hemolysis
PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0148413 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0176559 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Cytotoxic
PaperDe Novo Design and In Vitro Testing of Antimicrobial Peptides against Gram-Negative Bacteria PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0193634 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative Hemolytic
human blood cells
PaperDe Novo Design and In Vitro Testing of Antimicrobial Peptides against Gram-Negative Bacteria PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
RECORD: Rec_0271601 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Gram-negative bacteria: Escherichia coli ATCC 25922
3.125-6.25 μg/mL
MIC
PaperDe Novo Design and In Vitro Testing of Antimicrobial Peptides against Gram-Negative Bacteria PMID31163671 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31163671/
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