Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC366H595N103O97S8

DescriptionStandard

        MSVLHSILGVLALLSIVPQARTSFFKDTCSLETYNCRMKCNADERAIRYCSDWTICCKWRKTKLKKKKKW
    

Molecular Weight8246.79 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)9.53

Net Charge (pH 7.4) 9.15

Charge Density (pH 7.0) 0.1361

GRAVY Index-0.28

Hydrophobic Moment 0.67

Boman Index-0.12

Instability Index11.61

Aliphatic Index 79.43

Aromaticity 0.1000

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3286.94

LogP -28.22

H-bond Donors 126.0

H-bond Acceptors 116.0

Rotatable Bonds 281.0

Heavy Atoms 574.0

Ring Count 12.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062522 VERIFIED: NO

Provenance & Taxonomy

OrganismNeomonachus schauinslandi [Animal]

FamilyDefensin

Tax ID29088

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence