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MYP_124800
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Basic Information
Mucroporin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Antiviral ▸ Virucidal activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C85H138N18O20
Standard
Sequence
LFGLIPSLIGGLVSAFK
Physicochemical Analysis
1732.11 Da
8.75
0.76
0.55
0.0447
1.62
0.42
0.63
17.46
160.59
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
586.61
-1.89
20.0
21.0
55.0
123.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149927 VERIFIED: YES
Provenance & Taxonomy
Lychas mucronatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa AB93066
100 μg/mL
MIC
PMID20663230;18779362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20663230/
RECORD: Rec_0181042 VERIFIED: YES
Provenance & Taxonomy
Lychas mucronatus [Animal]
Scorpion venom peptide
172552
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
EC50
PaperVirucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses PMID21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21620914/
RECORD: Rec_0212375 VERIFIED: YES
Provenance & Taxonomy
Lychas mucronatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
B. thuringiensis AB92037
25 μg/mL
MIC
PaperMucroporin, the first cationic host defense peptide from the venom of Lychas mucronatus.
RECORD: Rec_0222721 VERIFIED: YES
Provenance & Taxonomy
Lychas mucronatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis AB91021
50
MIC
PaperMucroporin, the first cationic host defense peptide from the venom of Lychas mucronatus.
RECORD: Rec_0224102 VERIFIED: YES
Provenance & Taxonomy
Lychas mucronatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
25 μg/mL
MIC
PMID20663230;18779362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20663230/
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