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MYP_124800
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Basic Information
Mucroporin
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Antiviral ▸ Virucidal activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C85H138N18O20
Standard
Sequence
LFGLIPSLIGGLVSAFK
Physicochemical Analysis
1732.11 Da
8.75
0.76
0.55
0.0447
1.62
0.42
0.63
17.46
160.59
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
586.61
-1.89
20.0
21.0
55.0
123.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015956 VERIFIED: YES
Provenance & Taxonomy
Scorpiones [Animal]
Scorpion venom peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Virucidal Replication inhibitor
Measles virus (Replication); Vero
3.52 μM
EC50
PaperVirucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses. | Li Q, Zhao Z, Zhou D, Chen Y, Hong W, Cao L, Yang J, Zhang Y, Shi W, Cao Z, Wu Y, Yan H, Li W. | Peptides. 2011 | PMID:21620914 PMID21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21620914/
RECORD: Rec_0066424 VERIFIED: YES
Provenance & Taxonomy
Scorpiones [Animal]
Scorpion venom peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Virucidal Replication inhibitor
SARS coronavirus (Replication); MDCK
7.12 μM
EC50
PaperVirucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses. | Li Q, Zhao Z, Zhou D, Chen Y, Hong W, Cao L, Yang J, Zhang Y, Shi W, Cao Z, Wu Y, Yan H, Li W. | Peptides. 2011 | PMID:21620914 PMID21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21620914/
RECORD: Rec_0093103 VERIFIED: YES
Provenance & Taxonomy
Scorpiones [Animal]
Scorpion venom peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Virucidal Replication inhibitor
Influenza A virus (Replication); MDCK
1.03 μM
EC50
PaperVirucidal activity of a scorpion venom peptide variant mucroporin-M1 against measles, SARS-CoV and influenza H5N1 viruses. | Li Q, Zhao Z, Zhou D, Chen Y, Hong W, Cao L, Yang J, Zhang Y, Shi W, Cao Z, Wu Y, Yan H, Li W. | Peptides. 2011 | PMID:21620914 PMID21620914 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21620914/
RECORD: Rec_0131608 VERIFIED: YES
Provenance & Taxonomy
Lychas mucronatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus thuringiensis AB92037
25 μg/mL
MIC
PMID20663230;18779362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20663230/
RECORD: Rec_0133958 VERIFIED: YES
Provenance & Taxonomy
Lychas mucronatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis AB91021
50 μg/mL
MIC
PMID20663230;18779362 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20663230/
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