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MYP_124791
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Basic Information
Antimicrobial peptide P3-Hp-1891
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
19 amino acids
C86H154N24O23
Standard
Sequence
RLGTALPALLKTLLAGLNG
Physicochemical Analysis
1892.29 Da
11.00
1.76
1.55
0.0926
0.84
0.54
0.31
12.90
159.47
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
749.80
-6.06
26.0
25.0
62.0
133.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024905 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
17 μM
MIC
RECORD: Rec_0029163 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
25 μM
Hemolysis
PMID24717080 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24717080/
RECORD: Rec_0095760 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0108023 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
17 μM
MIC
PMID24717080 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24717080/
RECORD: Rec_0219096 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas pulchellus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
17 μM
MIC
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