Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC390H618N98O106S13

DescriptionStandard

        MRTCSVLPTVILLLTFTCLDKISASPFITVRYKYLNSSFLTFTQMPFDIRENNYPVPIRCRFCCGCCLMSVCGLCCE
    

Molecular Weight8792.52 Da

Isoelectric Point (pI)8.38

Net Charge (pH 7.0)2.41

Net Charge (pH 7.4) 2.03

Charge Density (pH 7.0) 0.0313

GRAVY Index0.60

Hydrophobic Moment 0.42

Boman Index0.17

Instability Index50.77

Aliphatic Index 91.04

Aromaticity 0.1169

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 5095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3237.75

LogP -27.39

H-bond Donors 124.0

H-bond Acceptors 122.0

Rotatable Bonds 278.0

Heavy Atoms 607.0

Ring Count 14.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0334865 VERIFIED: NO

Provenance & Taxonomy

OrganismFundulus heteroclitus [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal