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MYP_124752
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Basic Information
CIGB-300 (P15-Tat)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C124H212N52O29S3
Standard
Sequence
CWMSPRHLGTCGRKKRRQRRRPPQ
Physicochemical Analysis
2991.54 Da
12.00
8.83
8.54
0.3677
-1.95
0.60
-0.78
184.56
16.25
0.0417
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1362.70
-16.32
53.0
42.0
99.0
208.0
6.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H82
20±3 μM
IC50
PaperPubMed PMID: 15466209 PMID15466209 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15466209/
RECORD: Rec_0041204 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HeLa
136±16 μM
IC50
PaperPubMed PMID: 15466209 PMID15466209 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15466209/
RECORD: Rec_0046107 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Ca Ski
182±6 μM
IC50
PaperPubMed PMID: 15466209 PMID15466209 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15466209/
RECORD: Rec_0113630 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 15466209 PMID15466209 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15466209/
RECORD: Rec_0147929 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
201±16 μM
IC50
PaperPubMed PMID: 15466209 PMID15466209 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15466209/
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