Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC882H1359N221O249S12

DescriptionStandard

        MLNQCTSQQTDVLHGLALTYLSVSVQFSAPALSPTPERPIKLEIRFELHQVFWTPGSTGFCFPRTMRLLFLTFAILVFLPQVIPAYGGKKCWHKSGYCRKTCKADEVIKTACQHYQVCCVPAQKFPITSPTHIYNFLFDITDTMVTSLTTPSFEISTMNKENEKFDSELET
    

Molecular Weight19427.34 Da

Isoelectric Point (pI)7.57

Net Charge (pH 7.0)0.87

Net Charge (pH 7.4) 0.25

Charge Density (pH 7.0) 0.0051

GRAVY Index-0.02

Hydrophobic Moment 0.61

Boman Index0.11

Instability Index42.12

Aliphatic Index 78.66

Aromaticity 0.1170

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7460.17

LogP -74.27

H-bond Donors 263.0

H-bond Acceptors 267.0

Rotatable Bonds 622.0

Heavy Atoms 1364.0

Ring Count 39.0

Amide Bonds 183.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0052680 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris (Dog) [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin