Peptide Database

Peptide NameAlloferon (8-13)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC26H39N11O8

DescriptionStandard

        QHGVHG
    

Molecular Weight633.66 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0109

GRAVY Index-1.08

Hydrophobic Moment 0.33

Boman Index0.07

Instability Index-26.23

Aliphatic Index 48.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 309.27

LogP -4.06

H-bond Donors 10.0

H-bond Acceptors 10.0

Rotatable Bonds 19.0

Heavy Atoms 45.0

Ring Count 2.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0427009 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlloferon

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetCoxsackie virus B2(clinical strain):inhibition of virus replication in Hep-2 cells

Activity170 μM

MethodIC50

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