Peptide Database

Peptide NameVpr 65-79

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Reverse transcriptase inhibition

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC83H127N25O20S

DescriptionStandard

        QQLLFIHFRIGCQHS
    

Molecular Weight1827.12 Da

Isoelectric Point (pI)8.27

Net Charge (pH 7.0)0.92

Net Charge (pH 7.4) 0.61

Charge Density (pH 7.0) 0.0616

GRAVY Index0.14

Hydrophobic Moment 0.35

Boman Index0.13

Instability Index18.46

Aliphatic Index 104.00

Aromaticity 0.1333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 739.48

LogP -5.60

H-bond Donors 26.0

H-bond Acceptors 24.0

Rotatable Bonds 60.0

Heavy Atoms 129.0

Ring Count 4.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0341032 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

Targetinhibit the activity of Rnase H

Activity16.5 μM

MethodIC50

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