‹ ›
MYP_124603
← PREVIOUS NEXT → BACK
Basic Information
Cryptdin-4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
34 amino acids
C170H286N62O40S6
Standard
Sequence
LRGLLCYCRKGHCKRGERVRGTCGIRFLYCCPRR
Physicochemical Analysis
4030.87 Da
10.13
8.79
8.44
0.2584
-0.46
0.68
-0.35
28.05
65.88
0.0882
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1688.74
-16.76
71.0
56.0
135.0
278.0
5.0
33.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0055444 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
PaperMouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.
RECORD: Rec_0063552 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-31; 8-23; 13-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes EGD
PaperPubMed PMID: 15595831 | PubMed PMID: 7927786 | PubMed PMID: 16857681 PMID15595831;7927786;16857681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15595831/
RECORD: Rec_0119964 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
alpha-defensin family
10090; 0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
6-31; 8-23; 13-30
Bio-Activity Profile
Antimicrobial alpha-defensin family Antibacterial Host defense Defensin-like
PaperPDB 1TV0 structural record; NMR; chain A; residues 3-34
RECORD: Rec_0148937 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
10090
Structure & Mods
linear disulfide-stabilized peptide [Linear]
canonical L-amino-acid peptide [L]
6-31, 8-23, 13-30
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0253475 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
6-31; 8-23; 13-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML-35p
PaperPubMed PMID: 15595831 | PubMed PMID: 7927786 | PubMed PMID: 16857681 PMID15595831;7927786;16857681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15595831/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2