Peptide Database

Peptide Namevenom natriuretic peptide AsNP-a

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC154H258N48O53S3

DescriptionStandard

        SGSKTAKIGDGCFGVRIDRIGSTSGMGCGSVPKPTPGGS
    

Molecular Weight3726.18 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0626

GRAVY Index-0.26

Hydrophobic Moment 0.54

Boman Index0.05

Instability Index11.80

Aliphatic Index 47.44

Aromaticity 0.0256

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1601.28

LogP -26.06

H-bond Donors 59.0

H-bond Acceptors 59.0

Rotatable Bonds 122.0

Heavy Atoms 258.0

Ring Count 4.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0239604 VERIFIED: YES

Provenance & Taxonomy

OrganismAustrelaps superbus [Animal]

Familyvenom natriuretic peptide AsNP

Tax ID29156

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour