Peptide Database

Peptide NameDefensin-A4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC478H793N151O142S9

DescriptionStandard

        MKTLCLLFAVLCLVTWTQARGAEVEENLTAQDGEVDIAGDNGDVQLTLNTDDFESFTLKTLTLGHPRVKRHSCVCRRICAARQVRKGRCSRRRRICCLY
    

Molecular Weight11215.92 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)4.61

Net Charge (pH 7.4) 4.16

Charge Density (pH 7.0) 0.0466

GRAVY Index-0.18

Hydrophobic Moment 0.66

Boman Index-0.13

Instability Index42.12

Aliphatic Index 89.60

Aromaticity 0.0505

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4801.28

LogP -52.25

H-bond Donors 181.0

H-bond Acceptors 158.0

Rotatable Bonds 380.0

Heavy Atoms 780.0

Ring Count 9.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0103548 VERIFIED: NO

Provenance & Taxonomy

OrganismOrnithorhynchus anatinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence