‹ ›
MYP_124515
← PREVIOUS NEXT → BACK
Basic Information
Dm-AMP1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Plant bioactivity ▸ Plant defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
50 amino acids
C228H337N73O71S9
Standard
Sequence
ELCEKASKTWSGNCGNTGHCDNQCKSWEGAAHGACHVRNGKHMCFCYFNC
Physicochemical Analysis
5525.15 Da
7.80
1.11
0.61
0.0222
-0.69
0.51
-0.08
5.59
21.60
0.1000
12490.00
12990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2330.62
-31.11
88.0
85.0
180.0
381.0
11.0
55.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0123069 VERIFIED: YES
Provenance & Taxonomy
Dahlia merckii [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
NOTE: Medium B = Medium A supplemented with 1 mM CaCl2 and 50 mM KCI
PaperPubMed PMID: 13129623 | Isolation and characterisation of plant defensins from seeds of Asteraceae, Fabaceae, Hippocastanaceae and Saxifragaceae. FEBS Lett. 1995 Jul 17;368(2):257-262. doi: 10.1016/0014-5793(95)00666-W. PMID: 7628617. | PubMed PMID: 8663029 | PubMed PMID: 17216480 PMID13129623;7628617;8663029;17216480 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/13129623/
RECORD: Rec_0134326 VERIFIED: YES
Provenance & Taxonomy
Dahlia merckii [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Phosphorylation reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Botrytis cinerea
10 μg/mL
IC50
PaperPubMed PMID 7628617 | PubMed PMID 1460498 | PubMed PMID 20000000 | Mol Plant Microbe Interact. 2000;13:54-61 | Thevissen K et al 2000 PNAS USA 97: 9531-6 | Montesinos E 2007 FEMS Microbiol Lett 270, 1-11 PMID7628617;1460498;20000000;20000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7628617/
RECORD: Rec_0139028 VERIFIED: YES
Provenance & Taxonomy
Dahlia merckii [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
V. albo-atrum
4 μg/mL
IC50
PaperTransgenic expression in Arabidopsis of a polyprotein construct leading to production of two different antimicrobial proteins.
RECORD: Rec_0140534 VERIFIED: YES
Provenance & Taxonomy
Dahlia merckii [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
[Botrytis cinerea (
100 μg/mL
MIC
PMID7628617 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7628617/
RECORD: Rec_0142680 VERIFIED: YES
Provenance & Taxonomy
Dahlia merckii [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
[Botrytis cinerea (
1.5 μg/mL
MIC
PMID7628617 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7628617/
FIRST PREV 1 2 3 4 5 6 ... 12 NEXT LAST
Showing 5 records on this page · Page 4 of 12