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MYP_124471
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Basic Information
Cathelicidin 2 Cl, Cl-CATH2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
34 amino acids
C184H309N69O40
Standard
Sequence
LIQRGRFGRFLGRIRRFRPRINFDIRARGSIRLG
Physicochemical Analysis
4127.86 Da
12.00
9.76
9.56
0.2871
-0.51
0.92
-0.37
24.21
94.71
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1839.44
-17.08
71.0
50.0
142.0
293.0
5.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0294962 VERIFIED: YES
Provenance & Taxonomy
Columba livia [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 2002
37.5 μg/mL
MIC
PMID26194630 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26194630/
RECORD: Rec_0298271 VERIFIED: YES
Provenance & Taxonomy
Columba livia [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida glabrata 08A802
18.75 μg/mL
MIC
PMID26194630 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26194630/
RECORD: Rec_0301017 VERIFIED: YES
Provenance & Taxonomy
Columba livia [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
18.75 μg/mL
MIC
PMID26194630 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26194630/
RECORD: Rec_0312810 VERIFIED: YES
Provenance & Taxonomy
Columba livia [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus 08032706
18.75 μg/mL
MIC
PMID26194630 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26194630/
RECORD: Rec_0323042 VERIFIED: YES
Provenance & Taxonomy
Columba livia [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-inflammatory
Staphylococcus aureus ATCC 27853, Staphylococcus aureus 08032706, Staphylococcus aureus 08032712, Staphylococcus aureus 08032810, Staphylococcus aureus gz130623 , Bacillus cereus 1373
9.4-18.8 μg/mL
MIC
PaperNovel Cathelicidins from Pigeon Highlights Evolutionary Convergence in Avain Cathelicidins and Functions in Modulation of Innate Immunity
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