Peptide Database

Peptide NameUbiquitin-like protein ISG15

Function Ontology

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV ▸ Anti-HSV-1

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length161 amino acids

Chemical FormulaC788H1279N221O237S8

DescriptionStandard

        MAWDLKVKMLGGNDFLVSVTNSMTVSELKKQIAQKIGVPAFQQRLAHQTAVLQDGLTLSSLGLGPSSTVMLVVQNCSEPLSILVRNERGHSNIYEVFLTQTVDTLKKKVSQREQVHEDQFWLSFEGRPMEDKELLGEYGLKPQCTVIKHLRLRGGGGDQCA
    

Molecular Weight17897.44 Da

Isoelectric Point (pI)7.74

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.34

Charge Density (pH 7.0) 0.0052

GRAVY Index-0.23

Hydrophobic Moment 0.58

Boman Index0.01

Instability Index32.37

Aliphatic Index 93.73

Aromaticity 0.0559

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7416.20

LogP -75.13

H-bond Donors 256.0

H-bond Acceptors 250.0

Rotatable Bonds 613.0

Heavy Atoms 1254.0

Ring Count 20.0

Amide Bonds 178.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0417427 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyISG15

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsS-nitrosylation Cys144, Cys155

Bio-Activity Profile

Function

Antiviral Interferon pathway modulator Anti-SBV Anti-HSV-1

TargetSindbis virus(SBV)/herpes virus type 1 (HSV-1)