Peptide Database

Peptide NameAPP-C59

Function Ontology

Regulator of synapse formation

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC306H485N81O90S3

DescriptionStandard

        KKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQNIATVIVITLVML
    

Molecular Weight6834.81 Da

Isoelectric Point (pI)7.03

Net Charge (pH 7.0)0.03

Net Charge (pH 7.4) -0.35

Charge Density (pH 7.0) 0.0005

GRAVY Index-0.34

Hydrophobic Moment 0.57

Boman Index0.02

Instability Index28.96

Aliphatic Index 85.76

Aromaticity 0.0847

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2782.40

LogP -24.20

H-bond Donors 93.0

H-bond Acceptors 96.0

Rotatable Bonds 230.0

Heavy Atoms 480.0

Ring Count 10.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380873 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyAmyloid-beta

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Regulator of synapse formation

MethodPulse chase experiment

Half-LifeBHK cell line, in vitro; ~300 s