Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length194 amino acids

Chemical FormulaC986H1495N231O294S9

DescriptionStandard

        IDDLAEIDYSLNSLPAVFRPFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTCSFAYYTAGAFNITIAEEVSRTQRNGWLRTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTAEIQGSMEVFAVLPDSTTHSLFTMNIAANTSIALNIFDQKLMGSLCLNR
    

Molecular Weight21577.37 Da

Isoelectric Point (pI)4.26

Net Charge (pH 7.0)-11.16

Net Charge (pH 7.4) -11.50

Charge Density (pH 7.0) -0.0575

GRAVY Index0.24

Hydrophobic Moment 0.67

Boman Index0.22

Instability Index45.73

Aliphatic Index 92.58

Aromaticity 0.1340

Extinction Coeff. Reduced 21890.00

Extinction Coeff. Oxidized 22015.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8314.66

LogP -94.98

H-bond Donors 286.0

H-bond Acceptors 293.0

Rotatable Bonds 684.0

Heavy Atoms 1520.0

Ring Count 40.0

Amide Bonds 208.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063434 VERIFIED: NO

Provenance & Taxonomy

OrganismCalonectris borealis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria