Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length487 amino acids

Chemical FormulaC2428H3872N612O696S17

DescriptionStandard

        MFLWFVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTETVDPIGKVQYSFTGMQIVNLGLPKSALGLVPDTGVMLSIGNGYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTNDDTGHPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALCNALQKQICPLVADSSADINPHLKTLNVLAEVDQYAEIEYSMVGSPVISNTSIDLGLKGEFYNIGEHKEPPFSPIPFSFLSQDTDMIYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGTFIPQIEKMYPGLMMKLLVETVKEPLITFEPNNVTVQASSTVTAYAIQPNSTLSPLFVLNLVRLVQTIILLNRIDISLAKSYVGPFQVTSLDSIFTIVLKVAVIPKVNAHLQEGYPLPAIGKMQLVNSRLQVLKVSLCVCVYIYIYTYIHRCISINENVVENSFISVIQLKL
    

Molecular Weight53317.50 Da

Isoelectric Point (pI)8.36

Net Charge (pH 7.0)3.07

Net Charge (pH 7.4) 2.31

Charge Density (pH 7.0) 0.0063

GRAVY Index0.33

Hydrophobic Moment 0.68

Boman Index0.21

Instability Index24.85

Aliphatic Index 113.00

Aromaticity 0.0862

Extinction Coeff. Reduced 44810.00

Extinction Coeff. Oxidized 45185.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0349994 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria