Peptide Database

Peptide Namenatriuretic peptide PaNP-d

Function Ontology

Antimicrobial

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC160H260N44O56S3

DescriptionStandard

        SGSKTAEIDDGCFGLPLDPIGSTSGMGCRSVPKPIPGGS
    

Molecular Weight3792.23 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-1.56

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0399

GRAVY Index-0.18

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index36.32

Aliphatic Index 60.00

Aromaticity 0.0256

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1550.15

LogP -22.31

H-bond Donors 54.0

H-bond Acceptors 58.0

Rotatable Bonds 119.0

Heavy Atoms 263.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0133856 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudechis australis [Animal]

Familynatriuretic peptide PaNP

Tax ID8670

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0185975 VERIFIED: NO