Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC471H774N126O134S7

DescriptionStandard

        MKLLKVLIILLFVVLADGVQSKRCFNNVSGYCRKRCKLGEIAEVGCLHAKYCCVNELENKKHKVTQEPVQSKETSNGIQDEIVLPTATYFPITI
    

Molecular Weight10570.40 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0386

GRAVY Index0.05

Hydrophobic Moment 0.60

Boman Index0.05

Instability Index37.77

Aliphatic Index 105.64

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4212.78

LogP -36.18

H-bond Donors 149.0

H-bond Acceptors 147.0

Rotatable Bonds 361.0

Heavy Atoms 738.0

Ring Count 11.0

Amide Bonds 102.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0024813 VERIFIED: NO

Provenance & Taxonomy

OrganismMesocricetus auratus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10036

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic