Peptide Database

Peptide NameKiller protein of pyocin s3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC919H1468N250O274S3

DescriptionStandard

        PSQITVLPIPEKVGSDIESLPMPEEKDFRDYILILPIPNMPPVYVYLSKPPVKPLEVGEYHDLAGRSRNDGMDIDHIPSKGALKLFLKAKLGKAATDKDIDKILNSGVSIAIPHRIHRGYSETYKGRNTKAKQVKDALDIGAAIDSNFDAQVPGLRKEGYTDEQLNKAREELHQLNKEQGWYK
    

Molecular Weight20499.19 Da

Isoelectric Point (pI)7.45

Net Charge (pH 7.0)0.42

Net Charge (pH 7.4) 0.04

Charge Density (pH 7.0) 0.0023

GRAVY Index-0.61

Hydrophobic Moment 0.69

Boman Index-0.07

Instability Index42.69

Aliphatic Index 89.02

Aromaticity 0.0656

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8403.80

LogP -93.26

H-bond Donors 282.0

H-bond Acceptors 282.0

Rotatable Bonds 688.0

Heavy Atoms 1446.0

Ring Count 33.0

Amide Bonds 195.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325929 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus khanii subsp. guanajuatensis [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperPhotorhabdus khanii subsp. guanajuatensis subsp. nov., isolated from Heterorhabditis atacamensis, and Photorhabdus luminescens subsp. mexicana subsp. nov., isolated from Heterorhabditis mexicana entomopathogenic nematodes PMID30688647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30688647/