Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC428H676N124O127S10

DescriptionStandard

        MRTLAFLAALLLVTQAQAGPLQGRDEEMPPQEWPMAEDRDVSISITWNENSIPQAPVRSMACACRRPACLAGETRLGTCHFGNNVFVFCC
    

Molecular Weight9911.35 Da

Isoelectric Point (pI)5.19

Net Charge (pH 7.0)-2.45

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0272

GRAVY Index-0.01

Hydrophobic Moment 0.65

Boman Index0.06

Instability Index65.21

Aliphatic Index 76.00

Aromaticity 0.0667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3990.83

LogP -41.61

H-bond Donors 141.0

H-bond Acceptors 136.0

Rotatable Bonds 315.0

Heavy Atoms 689.0

Ring Count 16.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0305193 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocebus murinus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Fungicidal

MethodQualitative functional evidence