Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC450H714N132O137S14

DescriptionStandard

        MKTFSVAVAVAVVLTFICLQESSAVSFTEVQELEEPMSSEGAVAAFEEMSEESWKMPYNNRHKRSPAGRNSRRRRCRFCCGCCPNMIGCGTCCKF
    

Molecular Weight10614.20 Da

Isoelectric Point (pI)8.11

Net Charge (pH 7.0)1.52

Net Charge (pH 7.4) 1.10

Charge Density (pH 7.0) 0.0160

GRAVY Index-0.16

Hydrophobic Moment 0.43

Boman Index-0.05

Instability Index105.92

Aliphatic Index 53.37

Aromaticity 0.0842

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4342.30

LogP -50.23

H-bond Donors 162.0

H-bond Acceptors 154.0

Rotatable Bonds 351.0

Heavy Atoms 733.0

Ring Count 14.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084821 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal