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MYP_124195
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Basic Information
PR-39
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Wound healing/Regeneration ▸ Wound healing
Standard
39 amino acids
C229H345N69O41
Standard
Sequence
RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP
Physicochemical Analysis
4720.63 Da
12.00
9.76
9.55
0.2502
-1.31
0.62
-0.33
118.68
30.00
0.1538
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1641.34
-8.00
52.0
51.0
116.0
339.0
25.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0144412 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimalarial Antiparasitic
Plasmodium falciparum D10
ELISA (HRP-II levels detection)
PaperComprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon PMID18816382 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18816382/
RECORD: Rec_0146172 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Cathelicidin
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella Typhimurium LT2
1 μM
MIC
PMID1765098 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1765098/
RECORD: Rec_0150060 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
2.5 μM
MBC
PMID24755622 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24755622/
RECORD: Rec_0150706 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Natural peptide
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis H37Rv
9 μg/mL
IC50
PMID25681127 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25681127/
RECORD: Rec_0150816 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Natural peptide
9823
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial
Mycobacterium tuberculosis E1380/94 MDR (Isoniazid, rifampicin, streptomycin, ethambutol) strain
50 μg/mL
MIC
PMID11328767 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11328767/
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