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MYP_124187
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Basic Information
Halocidin precursorA
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C67H113N21O17S
Standard
Sequence
ALLHHGLNCAKGVLA
Physicochemical Analysis
1516.81 Da
8.28
0.96
0.65
0.0640
0.85
0.42
0.36
-5.16
143.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
597.19
-4.79
21.0
21.0
49.0
106.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0176050 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/12067731/ PMID12067731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067731/
RECORD: Rec_0197245 VERIFIED: YES
Provenance & Taxonomy
Halocynthia aurantium [Animal]
Halocidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
No hemolytic activity towards human erythrocytes
Hemolysis
PMID12067731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067731/
RECORD: Rec_0250267 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US7504380B2/en PatentUS 7504380 B2
RECORD: Rec_0296525 VERIFIED: YES
Provenance & Taxonomy
Halocynthia aurantium [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
PaperPubMed PMID: 12067731 PMID12067731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067731/
RECORD: Rec_0421683 VERIFIED: YES
Provenance & Taxonomy
Halocynthia aurantium [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PaperPubMed PMID: 12067731 PMID12067731 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12067731/
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