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MYP_124184
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Basic Information
Hymenochirin-10B
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
29 amino acids
C138H247N35O39
Standard
Sequence
IKIPPIVKDTLKKVAKGVLSTVADALSKS
Physicochemical Analysis
3020.65 Da
10.00
3.76
3.54
0.1295
0.32
0.69
0.10
-11.37
131.03
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1192.41
-9.96
41.0
43.0
104.0
212.0
2.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0070532 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus NCTC 8325
256-512 μM
MIC
PMID24466037 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24466037/
RECORD: Rec_0111813 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
04-8 μM
MIC
PMID24466037 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24466037/
RECORD: Rec_0202204 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655
1 μM
MIC
PMID24466037 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24466037/
RECORD: Rec_0232499 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
>512 μM
Hemolysis
PMID24466037 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24466037/
RECORD: Rec_0379114 VERIFIED: YES
Provenance & Taxonomy
Hymenochirus boettgeri [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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