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MYP_124178
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Basic Information
Gradimycin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
19 amino acids
C81H132N20O27S4
Standard
Sequence
SSGWVCTLTIECGTVICAC
Physicochemical Analysis
1946.29 Da
4.05
-1.58
-1.84
-0.0830
1.27
0.17
0.44
103.71
97.37
0.0526
5500.00
5750.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
741.36
-8.71
31.0
30.0
59.0
132.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002529 VERIFIED: YES
Provenance & Taxonomy
Actinoplanes garbadinensis [other]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus Sackman 10B CIBA
50 μg/mL
MIC
Paper8414 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ3367
RECORD: Rec_0025063 VERIFIED: YES
Provenance & Taxonomy
Actinoplanes garbadinensis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecium VanS L568
128 μg/mL
MIC
PaperGardimycin, a new antibiotic from Actinoplanes. III. Biological properties
RECORD: Rec_0029072 VERIFIED: YES
Provenance & Taxonomy
Actinoplanes garbadinensis [other]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Proteus rulgaris X 19H ATCC 881
100 μg/mL
MIC
Paper8414 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ3367
RECORD: Rec_0036048 VERIFIED: YES
Provenance & Taxonomy
Actinoplanes garbadinensis [other]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Trichophyton mentagrophytes SKF 17410
100 μg/mL
MIC
Paper8414 Evidence URLhttps://camp3.bicnirrh.res.in/seqDisp.php?id=CAMPSQ3367
RECORD: Rec_0037193 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
C-terminal thioether bridge is oxidated
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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